BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20250504T105259EDT-9782dZUbzo@132.216.98.100 DTSTAMP:20250504T145259Z DESCRIPTION:\nSupported by the generosity of the Killam Trusts\, The Neuro' s Killam Seminar Series invites outstanding guest speakers whose research is of interest to the scientific community at The Neuro and ºÚÁÏÉç Univers ity.\n\n\nRegister Now\n\nTo watch online\, click here\n\nHost: Jean-Franc ois Cloutier\n\n\nCharacterizing the Neural Circuitry Underlying Odorant P erception\n\nAbstract: The olfactory system's ability to detect and discri minate between the vast array of chemicals present in the environment is c ritical for an animal's survival. In mammals\, the first step of this odor processing is executed by olfactory sensory neurons\, which project their axons to a stereotyped location in the olfactory bulb (OB) to form glomer uli. The stereotyped positioning of glomeruli in the OB suggests an import ance for this organization in odor perception. However\, because the locat ion of only a limited subset of glomeruli has been determined\, it has bee n challenging to determine the relationship between glomerular location an d odor discrimination. Using a combination of single-cell RNA sequencing\, spatial transcriptomics and machine learning\, we have generated a map of most glomerular positions in the mouse OB. These observations significant ly extend earlier studies and suggest an overall organizational principle in the OB that may be used by the brain to assist in odor decoding. In add ition\, we have begun to characterize specific olfactory neural circuits t hat mediate particular innate\, odor-driven behaviors.\n\nPaul Greer\n\nAs sociate Professor\, University of Massachusetts Medical School\n\nPaul is a Massachusetts lifer\, never having lived outside of a two-mile radius fr om the hospital in which he was born. Despite this embarrassingly parochia l upbringing\, Paul has managed to experience a broad scientific training from a series of mentors to whom he remains incredibly grateful. For his d octoral work\, under Mike Greenberg’s mentorship\, he characterized mechan isms of synapse development and function relevant to human neurological di sorders. Upon graduating from Mike’s lab\, he joined Bob Datta’s lab\, and ever since he has been investigating the mechanisms by which mammals resp ond appropriately to exteroceptive and interoceptive chemical cues.\n DTSTART:20250401T200000Z DTEND:20250401T210000Z LOCATION:de Grandpre Communications Centre\, The Neuro SUMMARY:Killam Seminar Series: Characterizing the Neural Circuitry Underlyi ng Odorant Perception URL:/neuro/channels/event/killam-seminar-series-charac terizing-neural-circuitry-underlying-odorant-perception-364264 END:VEVENT END:VCALENDAR