BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20250630T153301EDT-4645sfO3Ik@132.216.98.100 DTSTAMP:20250630T193301Z DESCRIPTION:Leveraging genomics\, proteomics\, and other omics for drug tar get discovery in cardiometabolic diseases and complex traits: Toward bette r clinical care\n\nSatoshi Yoshiji\, \n Tuesday September 17\, 12-1pm\n Zoom Link: https://mcgill.zoom.us/j/89914150820\n In Person: 5 50 Sherbrooke\, Room 189\n \n Abstract: \n In this talk\, I will cover three topics: (i) Leveraging large-scale genomics and proteomics to identify dru g targets\; (ii) Disentangling the genetic heterogeneity of type 2 diabete s\; and (iii) A new multi-ancestry\, multi-omics biobank of 12\,500 indivi duals in Montreal.\n\nFirst\, I will describe our research that leverages large-scale genomics and proteomics to identify clinically actionable circ ulating proteins that link obesity to coronary artery disease\, stroke\, t ype 2 diabetes\, and COVID-19. Specifically\, I will explain how we identi fied circulating proteins that can be prioritized for drug development by integrating proteome-wide Mendelian randomization\, colocalization\, and s ingle-cell RNA sequencing. I will also discuss our ongoing work to generat e a multi-ancestry MR atlas of protein-disease associations\, a project I have undertaken with QLS PhD student Chen-Yang Su and colleagues. Second\, I will explain our efforts to disentangle the genetic heterogeneity of ty pe 2 diabetes through a new Bayesian approach. Finally\, I will describe a new multi-ancestry\, multi-omics biobank of 12\,500 individuals in Montre al\, dedicated to drug target discovery and precision medicine\, for which I serve as co-PI.\n\nShort Bio:\n Satoshi Yoshiji (pronounced “yo-she-gee” ) is an Assistant Professor in the Department of Human Genetics and a boar d-certified endocrinologist. His research goal is to use genomics\, proteo mics\, and other omics to identify drug targets and advance precision medi cine for diabetes\, obesity\, cardiovascular diseases\, and beyond. He is recruiting ambitious and forward-looking students. Webpage: https://yoshij i-lab.org/\n DTSTART:20240917T160000Z DTEND:20240917T170000Z SUMMARY:QLS Seminar Series - Satoshi Yoshiji URL:/qls/channels/event/qls-seminar-series-satoshi-yos hiji-358944 END:VEVENT END:VCALENDAR