Centre J.D. MacLean pour maladies tropicales - agrégateur /tropmed/fr/aggregator Centre J.D. MacLean pour maladies tropicales - flux agrégés fr Recent publications from TDC/Clinical Epidemiology authors: Estimated prevalence of hepatitis B and C among immigrants in Canada https://pubmed.ncbi.nlm.nih.gov/40861919/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250828013749&v=2.18.0.post9+e462414 CONCLUSION: This is the first study to estimate the burden of HBV and HCV among immigrants at the national level in Canada. The results show that the prevalence of viral hepatitis among immigrants is higher than the general Canadian population. However, grouping all immigrants into one category masks important variation, and potentially over-estimates the burden of HBV and HCV among immigrants. Strengthening our understanding of hepatitis prevalence among immigrants can improve our ability to... Wed, 27 Aug 2025 06:00:00 -0400 Recent publications from TDC/Clinical Epidemiology authors: Cutaneous larva migrans in Canadian travellers returning from the Caribbean: A 10-year surveillance analysis from CanTravNet https://pubmed.ncbi.nlm.nih.gov/40831490/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250821011317&v=2.18.0.post9+e462414 CONCLUSION: Proportions and absolute numbers of CLM in travellers returning to Canada from the Caribbean are increasing. Improved awareness of this common dermatosis among physicians and travellers, as well as improved access to effective therapies, will reduce associated morbidity. Wed, 20 Aug 2025 06:00:00 -0400 Recent publications from TDC/Clinical Epidemiology authors: Surveillance of single nucleotide polymorphisms correlated to macrocyclic lactone resistance in Dirofilaria immitis from client-owned dogs across the United States https://pubmed.ncbi.nlm.nih.gov/40779992/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250810020227&v=2.18.0.post9+e462414 Dirofilaria immitis is a parasitic filarial nematode and the causative agent of heartworm disease in canids and other species. Heartworm disease is predominantly managed via macrocyclic lactone (ML) - based chemoprophylactics. Through opportunistic sampling, genotypically and phenotypically confirmed ML-resistant D. immitis isolates have been isolated in the Lower Mississippi River Valley region (LMRV); however, the pervasiveness of resistant isolates in the USA has not been evaluated. This... Fri, 08 Aug 2025 06:00:00 -0400 Recent publications from TDC/Clinical Epidemiology authors: Malaria https://pubmed.ncbi.nlm.nih.gov/40768732/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250807001859&v=2.18.0.post9+e462414 No abstract Wed, 06 Aug 2025 06:00:00 -0400 Recent publications from TDC/Clinical Epidemiology authors: Measles Importations by International Travelers, GeoSentinel 2019-2025 https://pubmed.ncbi.nlm.nih.gov/40738382/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250731021112&v=2.18.0.post9+e462414 CONCLUSIONS: Against a background of increasing numbers of measles cases and outbreaks globally, GeoSentinel observed a stable trend of measles importations by international travelers. Measles caused considerable morbidity among travelers. Immunization effectively prevents measles in more than 97% of individuals. Pretravel consultations provide an important opportunity to promote vaccination coverage for all vaccine-preventable diseases, including measles. Wed, 30 Jul 2025 06:00:00 -0400 Recent publications from TDC/Clinical Epidemiology authors: Impacted subglottic fish vertebra in an infant: an unusual case report https://pubmed.ncbi.nlm.nih.gov/40727513/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250730011515&v=2.18.0.post9+e462414 Inhalation of foreign bodies, a common occurrence in children, can be life-threatening. Different types of foreign bodies can be found, but laryngeal localization is rare. We here report the case of an 8-month-old male infant who presented with respiratory distress, dysphonia, and stridor. On admission, the child exhibited severe laryngeal dyspnea. Cervical CT scan revealed a radiopaque foreign body in the larynx. Endoscopic extraction revealed an impacted fish vertebra in the subglottis.... Tue, 29 Jul 2025 06:00:00 -0400 Recent publications from TDC/Clinical Epidemiology authors: Integrative Modeling of Urinary Metabolomics and Metal Exposure Reveals Systemic Impacts of Electronic Waste in Exposed Populations https://pubmed.ncbi.nlm.nih.gov/40710556/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250727004612&v=2.18.0.post9+e462414 Background: Informal electronic waste (e-waste) recycling practices release a complex mixture of pollutants, particularly heavy metals, into the environment. Chronic exposure to these contaminants has been linked to a range of health risks, but the molecular underpinnings remain poorly understood. In this study, we investigated the alterations in metabolic profiles due to e-waste exposure and linked these metabolites to systemic biological effects. Methods: We applied untargeted high-resolution... Fri, 25 Jul 2025 06:00:00 -0400 Recent publications from TDC/Clinical Epidemiology authors: Early-life RSV infection modulates innate immune events, preferentially enhancing allergen-induced type 2 lung inflammation in females https://pubmed.ncbi.nlm.nih.gov/40690502/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250722003841&v=2.18.0.post9+e462414 Respiratory syncytial virus (RSV) causes millions of hospitalizations and thousands of deaths per year globally. Early-life RSV infection is also associated with the subsequent development of wheezing and asthma, which exhibits sex-related disparities in incidence, epidemiology, and morbidity. The mechanisms that underlie these sex-specific effects are not clear. We have developed a combined infection-allergy model in which 10-day old mice are infected with RSV and subsequently exposed to a... Mon, 21 Jul 2025 06:00:00 -0400 Recent publications from TDC/Clinical Epidemiology authors: Canadian Antibiotic Prescribing for Sepsis (CAPS) Study: A <em>Post Hoc</em> Analysis of the FABLED Cohort Study https://pubmed.ncbi.nlm.nih.gov/40672715/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250718005619&v=2.18.0.post9+e462414 CONCLUSIONS: Empiric therapies for septic patients in Canada were overly broad given the rare isolation of drug-resistant pathogens. Though likely confounded by severity of illness, optimal outcomes were observed when therapy was appropriate relative to the causative pathogen and infectious focus. Thu, 17 Jul 2025 06:00:00 -0400 Recent publications from TDC/Clinical Epidemiology authors: Severe Malaria in Travelers-Time to Create a Specific Definition https://pubmed.ncbi.nlm.nih.gov/40667864/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250717010041&v=2.18.0.post9+e462414 No abstract Wed, 16 Jul 2025 06:00:00 -0400